Biological Information
Background Information:
The Ready-to-Assay Chem-6 Parental Control Frozen Cells are a convenient, thaw and use format of the Chem-6 cells used to create ChemiSCREEN™ cell lines. These cells lack most endogenous GPCR expression, and express high levels of the promiscuous G protein Gα15, allowing forced coupling of any class of GPCR to calcium signaling pathways. These ready-to-assay cells are intended for use as a negative control alongside the corresponding ready-to-assay GPCR-expressing cells. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format.
Target Class:
GPCR
Cell Background:
Chem-6
Usage
Product Type:
Frozen Cells
Application:
Drug Discovery & Development
Storage Conditions:
Short term (24 h) in vapor phase of liquid nitrogen. Media at 4°C.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Type:
Cell Based
Assay Measures:
Calcium Flux
Detection Method:
Fluorescence
Additional Information
Brand:
ChemiSCREEN™