PTPN22, active

N-terminal GST-tagged recombinant, human PTPN22 amino acids 1-312.

Catalog #: 14-768


Biological Information
Background Information:
PTPN22 (Protein Tyrosine Phosphatase Non-Receptor Type 22) is a member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. This protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. GenBank NM_015967
Target Class:
Accession Number:
Refer to CoA for Accession Number
Target Name:
Target Species:
Product Type:
Drug Discovery & Development
Storage Conditions:
1 year at -70°C
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14-768x Datasheet

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