| Biological Information | |
|---|---|
| Background Information: | PTPN22 (Protein Tyrosine Phosphatase Non-Receptor Type 22) is a member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. This protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease.
GenBank NM_015967 |
| Target Class: | Phosphatase |
| Accession Number: | Refer to CoA for Accession Number |
| Target Name: | PTPN22 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 1 year at -70°C |
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PTPN22, active
N-terminal GST-tagged recombinant, human PTPN22 amino acids 1-312.
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14-768x Datasheet
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