PTPMEG-2

Background Information:

PTPMEG-2 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis. GenBank NM_002833

Target Class:

Phosphatase

Family:

Non-Receptor

Sub Family:

Protein Tyrosine

Protein Name:

PTPMEG2

Accession Number:

NM_002833.2

UniProt Number:

P43378

Gene Name:

PTPN9

Gene ID:

5780

Gene Aliases:

MEG2

Target Species:

Human