Biological Information | |
---|---|
Background Information: | The PrecisION® hnAChR α1/β1/δ/ε Recombinant Stable Cell Line is a stable, engineered cell line for use in studying nAChR α1/β1/δ/ε ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses nAChR α1/β1/δ/ε ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. |
Target Class: | Ion Channel |
Family: | Ligand-Gated Nicotinic Receptor |
Accession Number: | NM_000079/NM_000747/NM_000751/NM_000080 |
Target Name: | nAChR α1/β1/δ/ε |
Target Aliases: | acetylcholine receptor subunit alpha, Achr-1, cholinergic receptor, nicotinic, alpha 1 (muscle), cholinergic receptor, nicotinic alpha 1, cholinergic receptor, nicotinic, alpha 1, cholinergic receptor |
Target Species: | Human |
Usage | |
Product Type: | Stable Cell Lines |
Application: | Drug Discovery & Development |
Storage Conditions: | Store in vapor phase of liquid nitrogen. |
Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
Assay Information | |
Assay Measures: | Electrophysiology |
Additional Information | |
Brand: | PrecisION® |
PrecisION® hnAChR alpha1/beta1/delta/epsilon Recombinant Stable Cell Line
The PrecisION® hnAChR α1/β1/δ/ε Recombinant Stable Cell Line measures nAChR α1/β1/δ/ε ion channel activity via electrophysiological measurements. This cell line ships as two vials of cryopreserved cells.
User Manuals & Protocols
70-430 PrecisION Ion Channel Cell Lines_Rev_2.0
View DocumentDatasheets
CYL3052 Datasheet
View Document