Biological Information
Background Information:
The PrecisION™ hKv7.4 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying Kv7.4 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses Kv7.4 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques.
This stable engineered cell line is provided as two vials of cryopreserved cells.
Target Class:
Ion Channel
Family:
Potassium
Sub Family:
Voltage-Gated
Protein Name:
Kv7.4
Accession Number:
NM_004700.3
UniProt Number:
P56696
Gene Name:
KCNQ4
Gene ID:
9132
Gene Aliases:
Kv7.4
Target Species:
Human
Cell Background:
HEK293
Usage
Product Type:
Stable Cell Lines
Application:
Drug Discovery & Development
Storage Conditions:
Store in vapor phase of liquid nitrogen.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Type:
Cell Based
Assay Measures:
Electrophysiology
Detection Method:
Electrophysiology
Additional Information
Brand:
PrecisION™