Biological Information | |
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Background Information: | The PrecisION® hKv4.3/hKChIP1 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying Kv4.3/KChIP1 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses Kv4.3/KChIP1 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. |
Target Class: | Ion Channel |
Family: | Voltage-Gated Potassium Ion Channel |
Target Name: | Kv4.3/KChIP1 |
Target Aliases: | KCND3L, KCND3S, KSHIVB, Potassium voltage-gated channel subfamily D member 3, potassium voltage-gated channel, Shal-related subfamily, member 3, potassium channel, voltage gated Shal related subfamily D, member 3, potassium channel, voltage-gated Shal-related subfamily D, member 3, potassium voltage-gated channel, Shal-related family, member 3, potassium voltage-gated channel |
Target Species: | Human |
Usage | |
Product Type: | Stable Cell Lines |
Application: | Drug Discovery & Development |
Storage Conditions: | Store in vapor phase of liquid nitrogen. |
Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
Assay Information | |
Assay Measures: | Electrophysiology |
Additional Information | |
Brand: | PrecisION® |
PrecisION® hKv4.3/hKChIP1 Recombinant Stable Cell Line
The PrecisION® hKv4.3/hKChIP1 Recombinant Stable Cell Line measures Kv4.3/KChIP1 ion channel activity via electrophysiological measurements. This cell line ships as two vials of cryopreserved cells.
User Manuals & Protocols
70-430 PrecisION Ion Channel Cell Lines_Rev_2.0
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CYL3027 Datasheet
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