| Biological Information | |
|---|---|
| Background Information: | The PrecisION®® hGABAA α1/β3/γ2 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying GABAA α1/β3/γ2 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses GABAA α1/β3/γ2 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. |
| Target Class: | Ion Channel |
| Family: | Ligand-Gated GABAA receptors |
| Target Name: | GABAA α1/β3/γ2 |
| Target Aliases: | EJM5 | gamma-aminobutyric acid receptor subunit alpha-1 | Gabra-1 | gamma-aminobutyric acid (GABA) A receptor, alpha 1 | gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 | gamma-aminobutyric acid (GABA) A receptor | gamma-aminobutyric acid type A receptor alpha1 subunit |
| Target Species: | Human |
| Usage | |
| Product Type: | Stable Cell Lines |
| Application: | Drug Discovery & Development |
| Storage Conditions: | Short term (24 h): Store in vapor phase of liquid nitrogen. |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
| Assay Information | |
| Assay Measures: | Electrophysiology |
| Additional Information | |
| Brand: | PrecisION® |
PrecisION® hGABAA alpha1/beta3/gamma2 Recombinant Stable Cell Line
The PrecisION®® hGABAA α1/β3/γ2 Recombinant Stable Cell Line measures GABAA α1/β3/γ2 ion channel activity via electrophysiological measurements. This cell line ships as two vials of cryopreserved cells.
User Manuals & Protocols
70-430 PrecisION Ion Channel Cell Lines_Rev_2.0
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CYL3053 Datasheet
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