| Biological Information | |
|---|---|
| Background Information: | The PrecisION®® hERG Recombinant Stable Cell Line is a stable, engineered cell line for use in studying hERG ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses hERG ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. |
| Target Class: | Ion Channel |
| Family: | Voltage-Gated Potassium Ion Channel |
| Target Name: | hERG |
| Target Aliases: | eag-related protein 1 | erg1 | ERG-1 | ether-a-go-go-related gene potassium channel 1 | ether-à-go-go-related gene | HERG | potassium channel, voltage gated eag related subfamily H, member 2 | potassium voltage-gated channel | potassium voltage-gated channel, subfamily H (eag-related), member 2 |
| Target Species: | Human |
| Usage | |
| Product Type: | Stable Cell Lines |
| Application: | Drug Discovery & Development |
| Storage Conditions: | Short term (24 h): Store in vapor phase of liquid nitrogen. |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
| Assay Information | |
| Assay Measures: | Electrophysiology |
| Additional Information | |
| Brand: | PrecisION® |
PrecisION® hERG Recombinant Stable Cell Line
The PrecisION®® hERG Recombinant Stable Cell Line measures hERG ion channel activity via electrophysiological measurements. This cell line ships as two vials of cryopreserved cells.
User Manuals & Protocols
70-430 PrecisION Ion Channel Cell Lines_Rev_2.0
View DocumentDatasheets
CYL3039 Datasheet
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