PKC theta, active

C-terminal 6His-tagged recombinant, human full length PKC theta. PKC Lipid activator (Catalog # 20-133) is required for use.

Catalog #: 14-444


Biological Information
Background Information:
Protein kinase C, theta (PKCtheta, PRKCQ, PRKCT) is one of the major protein kinase C isoforms of a family of serine/threonine protein kinases. Breakdown of phosphatidylinositol leads to formation of diacylglycerol and inositol triphosphate, the former acting synergistically with Ca2+ to activate protein kinase C (PKC), resulting in translocation of the enzyme from cytosol to the membrane. Phosphorylation of proteins by PKC has been implicated as a pivotal regulatory element in signal transduction, cellular regulation, and with a high affinity to phorbol ester tumor promoters. GenBank L07032
Target Class:
Accession Number:
Target Name:
Target Aliases:
PRKCQ, OTTHUMP00000043365, MGC126514, OTTHUMP00000043364, MGC141919, PRKCT, nPKC-theta
Target Species:
Product Type:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
Usage Disclaimer:
These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit for a list of products that are governed by limited use label license terms and relevant patent and trademark information.


14-444x Datasheet

View Document