PKC iota, active

N-terminal 6His-tagged recombinant, human full length PKC iota PKC Lipid activator (Catalog # 20-133) is required for use.

Catalog #: 14-505


Biological Information
Background Information:
Protein kinase C, iota (PKCiota, PRKCI) is one of the major protein kinase C isoforms of a family of serine/threonine protein kinases. Breakdown of phosphatidylinositol leads to formation of diacylglycerol and inositol triphosphate, the former acting synergistically with Ca2+ to activate protein kinase C (PKC), resulting in translocation of the enzyme from cytosol to the membrane. Phosphorylation of proteins by PKC has been implicated as a pivotal regulatory element in signal transduction, cellular regulation, and with a high affinity to phorbol ester tumor promoters. GenBank NM_002740
Target Class:
Accession Number:
Target Name:
Target Aliases:
PRKCI, DXS1179E, MGC26534, PRKC-lambda/iota, PKCI, aPKC-lambda/iota, nPKC-iota
Target Species:
Product Type:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
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14-505x Datasheet

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