| Biological Information | |
|---|---|
| Background Information: | Protein kinase C h (PKCh) is one of the major protein kinase C isoforms of a family of serine/threonine protein kinases. Breakdown of phosphatidylinositol leads to formation of diacylglycerol and inositol triphosphate, the former acting synergistically with Ca2+ to activate protein kinase C (PKC), resulting in translocation of the enzyme from cytosol to the membrane. Phosphorylation of proteins by PKC has been implicated as a pivotal regulatory element in signal transduction, cellular regulation, and with a high affinity to phorbol ester tumor promoters.
GenBank NM_006255. Translation conflicts with NM_006255, V108L and G109R reported in dbEST BG719560 and BM549890, and L392Q reported in dbEST BI913495, BQ051772 and AU136862. |
| Target Class: | Kinase |
| Accession Number: | NM_006255.3 |
| Target Name: | PKCη |
| Target Aliases: | PRKCH, PRKCL, PKCL, MGC26269, nPKC-eta, MGC5363, PKC-L |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
PKC eta, active
N-terminal 6His-tagged recombinant, human PKC eta amino acids 2-end. PKC Lipid activator (Catalog # 20-133) is required for use.
Datasheets
14-497x Datasheet
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