Pim-3, active

Background Information:

Pim-3 (Proviral integration site for Moloney murine leukemia virus 3) is a serine/threonine protein kinase that belongs to the Pim family of kinases. It is involved in a variety of cellular processes, including cell proliferation, survival, differentiation, and metabolism. Research has suggested that Pim-3 plays a role in several diseases, including cancer, cardiovascular diseases, and inflammatory disorders. It has been shown to promote cancer cell proliferation and survival, and inhibition of Pim-3 has been suggested as a potential cancer therapy. Additionally, Pim-3 has been implicated in the regulation of T-cell development and function, making it a potential target for the treatment of autoimmune diseases and graft-versus-host disease.

Target Class:

Kinase

Family:

CAMK

Sub Family:

Protein Ser/Thr

Protein Name:

Pim3

Accession Number:

NM_001001852.2

UniProt Number:

Q86V86

Gene Name:

PIM3

Gene ID:

415116

Target Species:

Human