PI3 Kinase (p110alpha/p85alpha), active

Background Information:

Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. GenBank U79143 / GenBank XM_043865

Target Class:

Kinase

Family:

PtdIns(4,5)P 3-Kinase

Sub Family:

Lipid

Protein Name:

PI3Kalpha

Protein Aliases:

PI3K-alpha|PI3Kalpha|PtdIns-3-kinase subunit alpha|Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha|PtdIns-3-kinase subunit p110-alpha|p110alpha|Phosphoinositide-3-kinase catalytic alpha polypeptide|Serine/threonine protein kinase PIK3CA

Accession Number:

NM_006218.2

UniProt Number:

P42336

Gene Name:

PIK3CA

Gene ID:

5290

Gene Aliases:

PI3K

Target Species:

Human