PathHunter® U2OS GHSR Bioassay Kit

The PathHunter® U2OS GHSR Bioassay kit provides a robust, highly sensitive, and easy-to-use functional cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand based activation of GHSR GPCR via detection of β-arrestin recruitment.

Catalog #: 93-0242Y3-00141

$1,989.00 – $8,979.00

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Biological Information
Background Information:
The PathHunter® U2OS GHSR Bioassay kit provides a robust, highly sensitive, and easy-to-use functional cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand based activation of GHSR GPCR via detection of β-arrestin recruitment. The included cells overexpress ProLink-tagged GHSR and EA-tagged β-Arrestin-2. Activation of GHSR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates.
Target Class:
GPCR
Family:
Ghrelin Receptor
Accession Number:
NM_198407
Target Name:
GHSR
Target Aliases:
Ghrelin Receptor, GHDP
Target Species:
Human
Cell Background:
U2OS
Usage
Product Type:
Bioassay Kits
Application:
Potency; Commercial Release & Stability
Kit Components:
Storage Conditions:
Store in vapor phase of liquid nitrogen.
Usage Disclaimer:
These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Type:
Functional
Assay Measures:
β-Arrestin Recruitment
Detection Method:
Chemiluminescence
Additional Information
Brand:
PathHunter®

User Manuals & Protocols

70-418 PathHunter U2OS GHSR Bioassay Kit User Manual REV0

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Datasheets

93-0242Y3x Datasheet

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