PathHunter® eXpress VISTA/VISTA Dimerization Assay

The PathHunter® eXpress VISTA/VISTA Dimerization Assay measures ligand-induced dimerization of VISTA/VISTA. eXpress kits contain all assay materials: cells, reagents, and plates.

Catalog #: 93-1079E3CP5L


Biological Information
Background Information:
The PathHunter® VISTA/VISTA Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand induced dimerization of VISTA/VISTA receptors. This product uses EFC technology. The cells included overexpress VISTA target protein fused to PK alongside VISTA target protein fused to EA. Upon ligand-induced dimerization of VISTA/VISTA, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.
Target Class:
Checkpoint Receptor
T cell Receptor (inhibitory)
Accession Number:
Target Name:
Target Aliases:
VSIR, V-set immunoregulatory receptor, B7H5, GI24, B7-H5, Dies1, PD-1H, SISP1, VISTA, PP2135, C10orf54, DD1alpha
Target Species:
Cell Background:
Product Type:
eXpress Assay Kits
Drug Discovery & Development
Storage Conditions:
Store in vapor phase of liquid nitrogen.
Usage Disclaimer:
Ready-to-use eXpress assay kits are intended for in vitro research purposes only. These kits are not suitable for lot release applications. Refer to the ready-to-use bioassay kit format for potency testing in lot release for biologic therapeutics. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Type:
Assay Measures:
Detection Method:
Clinical Relevance
Therapeutic Area:
Additional Information

User Manuals & Protocols

70-301 PathHunter eXpress Dimerization Assay Kit REV3 User Manual

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93-1079E3x Datasheet

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