The PathHunter® IL17RD/TNFR2 Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. TNFα) induced dimerization of IL17RD/TNFR2 receptors. This product uses EFC technology. The cells included overexpress IL17RD target protein fused to PK alongside TNFR2 target protein fused to EA. Upon ligand-induced dimerization of IL17RD/TNFR2, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.
IL-17 Receptor Family
HH18, IL-17RD, IL17RLM, SEF, Interleukin-17 receptor D precursor
eXpress Assay Kits
Drug Discovery & Development
Store in vapor phase of liquid nitrogen.
Ready-to-use eXpress assay kits are intended for in vitro research purposes only. These kits are not suitable for lot release applications. Refer to the ready-to-use bioassay kit format for potency testing in lot release for biologic therapeutics. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
PathHunter® eXpress IL17RD/TNFR2 Dimerization Assay
The PathHunter® eXpress IL17RD/TNFR2 Dimerization Assay measures ligand-induced dimerization of IL17RD/TNFR2. eXpress kits contain all assay materials: cells, reagents, and plates.