PathHunter® eXpress IL17RA/IL17RC Dimerization Assay

The PathHunter® eXpress IL17RA/IL17RC Dimerization Assay measures ligand-induced dimerization of IL17RA/IL17RC. eXpress kits contain all assay materials: cells, reagents, and plates.

Catalog #: 93-0931E1CP7L


Biological Information
Background Information:
The PathHunter® IL17RA/IL17RC Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. IL-17a) induced dimerization of IL17RA/IL17RC receptors. This product uses EFC technology. The cells included overexpress IL17RC target protein fused to PK alongside IL17RA target protein fused to EA. Upon ligand-induced dimerization of IL17RA/IL17RC, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.
Target Class:
Cytokine Receptor
IL-17 Receptor Family
Accession Number:
Target Name:
Target Aliases:
IL-17R, IL-17 Receptor, IL17 Receptor, Interleukin 17 receptor A, CTLA-8, CTLA8, IL-17, IL-17A, IL17, ILA17
Target Species:
Cell Background:
Product Type:
eXpress Assay Kits
Drug Discovery & Development
Storage Conditions:
Store in vapor phase of liquid nitrogen.
Usage Disclaimer:
Ready-to-use eXpress assay kits are intended for in vitro research purposes only. These kits are not suitable for lot release applications. Refer to the ready-to-use bioassay kit format for potency testing in lot release for biologic therapeutics. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Type:
Assay Measures:
Detection Method:
Clinical Relevance
Therapeutic Area:
Additional Information

User Manuals & Protocols

70-301 PathHunter eXpress Dimerization Assay Kit REV3 User Manual

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93-0931E1x Datasheet

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