PathHunter® eXpress IL10RA/IL10RB Dimerization Assay

The PathHunter® eXpress IL10RA/IL10RB Dimerization Assay measures ligand-induced dimerization of IL10RA/IL10RB. eXpress kits contain all assay materials: cells, reagents, and plates.

Catalog #: 93-0985E3CP0L


Biological Information
Background Information:
The PathHunter® IL10RA/IL10RB Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. IL-10) induced dimerization of IL10RA/IL10RB receptors. This product uses EFC technology. The cells included overexpress IL10RA target protein fused to PK alongside IL10RB target protein fused to EA. Upon ligand-induced dimerization of IL10RA/IL10RB, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.
Target Class:
Cytokine Receptor
Type II Cytokine Receptor
Accession Number:
Target Name:
Target Aliases:
IL-10R, IL-10 Receptor, IL-10R, IL10R, Interleukin 10 receptor, alpha, CD210, CD210a, CDW210A, HIL-10R, IL-10R1, IL10R, IL10RA- CD210, IL10R, CD210a, CDW210A, HIL-10R, IL-10R1/ IL10RB CRFB4, CRF2-4, D21S58, D21S66, CDW210B, IL-10R2, IL-10RB
Target Species:
Cell Background:
Product Type:
eXpress Assay Kits
Drug Discovery & Development
Storage Conditions:
Store in vapor phase of liquid nitrogen.
Usage Disclaimer:
Ready-to-use eXpress assay kits are intended for in vitro research purposes only. These kits are not suitable for lot release applications. Refer to the ready-to-use bioassay kit format for potency testing in lot release for biologic therapeutics. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Type:
Assay Measures:
Detection Method:
Clinical Relevance
Therapeutic Area:
Additional Information

User Manuals & Protocols

70-301 PathHunter eXpress Dimerization Assay Kit REV3 User Manual

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93-0985E3x Datasheet

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