PathHunter® CHO-K1 NPY2R Bioassay Kit

Awaiting product image

The PathHunter® CHO-K1 NPY2R Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. peptide YY) based activation of NPY2R GPCR activity via detection of β-arrestin recruitment.

Catalog #: 93-0212Y2-00065

$1,989.00 – $8,979.00

Inquire
Biological Information
Background Information:
The PathHunter® CHO-K1 NPY2R Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. peptide YY) based activation of NPY2R GPCR via detection of β-arrestin recruitment. The included cells overexpress ProLink-tagged NPY2R and EA-tagged β-Arrestin-2. Activation of NPY2R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates.
Target Class:
GPCR
Family:
Neuropeptide Y Receptors
Sub Family:
Class A
Accession Number:
AY236540
Target Name:
NPY2R
Target Aliases:
Neuropeptide Y receptor Y2, NPY2-R, Neuropeptide Y2 receptor
Target Species:
Human
Cell Background:
CHO-K1
Usage
Product Type:
Bioassay Kits
Application:
Potency; Commercial Release & Stability
Kit Components:
Storage Conditions:
Store in vapor phase of liquid nitrogen.
Usage Disclaimer:
These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Type:
Functional
Assay Measures:
β-Arrestin Recruitment
Detection Method:
Chemiluminescence
Additional Information
Brand:
PathHunter®

User Manuals & Protocols

70-290 PathHunter GPCR Bioassay Kit REV11 User Manual

View Document

Datasheets

93-0212Y2x Datasheet

View Document