PathHunter® CHO-K1 mCCKAR β-Arrestin Cell Pool

The PathHunter® mCCKAR Cell Pool is a stable, engineered cell pool for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell pool enables assessment of ligand (e.g. cholecystokinin) based activation of mCCKAR GPCR activity via detection of β-arrestin recruitment.

Catalog #: 93-0598P2 Size: 2 vials
Inquire
Biological Information
Background Information:
The PathHunter® mCCKAR Cell Pool is a stable, engineered cell pool for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell pool enables assessment of ligand (e.g. cholecystokinin) based activation of mCCKAR GPCR activity via detection of β-arrestin recruitment. The included cell pool overexpresses ProLink-tagged mCCKAR and EA-tagged β-Arrestin-2. Activation of mCCKAR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable cell pool is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein
Target Class:
GPCR
Family:
Cholecystokinin Receptors
Accession Number:
NM_009827.2
Target Name:
CCKAR (CCK1 receptor)
Target Aliases:
Cholecystokinin A receptor
Target Species:
Mouse
Cell Background:
CHO-K1
Usage
Product Type:
Cell Pool
Application:
Drug Discovery & Development
Storage Conditions:
Store in vapor phase of liquid nitrogen.
Usage Disclaimer:
These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Type:
Functional
Assay Measures:
β-Arrestin Recruitment
Detection Method:
Chemiluminescence
Additional Information
Brand:
PathHunter®

User Manuals & Protocols

70-247 PathHunter Beta-Arrestin Assay for GPCR Cell Lines REV5 User Manual

View Document

Datasheets

93-0598P2 Datasheet

View Document
PathHunter® Detection Kit
93-0001
Inquire
AssayComplete™ Cell Plating 2 Reagent
93-0563R2A
100 mL

$339.00

AssayComplete™ Freezing Reagent F2
92-5102FR
2 x 50 mL

$339.00

AssayComplete™ Thawing Reagent T2
92-4102TR
100 mL

$249.00

AssayComplete™ Cell Detachment Reagent
92-0009
50 mL

$109.00

AssayComplete™ Cell Culture Kit-107
92-3107G
Kit

$397.00

AssayComplete™ G418
92-0030
20 mL

$239.00