The PathHunter® cyno GPR120 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. free fatty acids) based activation of GPR120 GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology. The included cell line overexpresses PK-tagged cyno GPR120 and EA-tagged β-Arrestin 2. Activation of GPR120 stimulates the recruitment of β-Arrestin 2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Cyno version of the protein.
G-protein coupled receptor 120
Stable Cell Lines
Drug Discovery & Development
Store in vapor phase of liquid nitrogen.
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PathHunter® CHO-K1 cyno GPR120 β-Arrestin Cell Line
The PathHunter® CHO-K1 cyno GPR120 β-Arrestin Cell Line measures GPR120 (GPCR) activity via recruitment of β-Arrestin2. This cell line ships as two vials of cryopreserved cells. Cyno protein.
User Manuals & Protocols