Biological Information

Background Information:

MRCKβ, also called CDC42 Binding Protein Kinase Beta, is a member of the serine/threonine protein kinase family. The protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization. [provided by RefSeq, Jul 2008]

Target Class:

Kinase

Family:

AGC

Sub Family:

Protein Ser/Thr

Protein Name:

MRCKbeta

Protein Aliases:

CDC42-binding protein kinase beta|CDC42BP-beta|DMPK-like beta|Myotonic dystrophy kinase-related CDC42-binding kinase beta|MRCK beta|Myotonic dystrophy protein kinase-like beta

Accession Number:

NM_006035.3

UniProt Number:

Q9Y5S2

Gene Name:

CDC42BPB

Gene ID:

9578

Gene Aliases:

MRCKB|KIAA1124

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

6 months at -70°C

Usage disclaimer:

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Assay Information

Assay Type:

Enzymatic

Clinical Relevance

Therapeutic Area:

Oncology/Immuno-Oncology