MYLK (myosin light polypeptide kinase; myosin light chain kinase, MLCK), which belongs to the family of Ca2+/calmodulin (CaM)-dependent protein kinases, induces a high degree of myosin motor activity by specifically phosphorylating the myosin II regulatory light chain (MRLC). Myosin II phosphorylation is involved in smooth muscle contraction and cell motility in non-muscle cells. GenBank NM_053025
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Drug Discovery & Development
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