Biological Information

Background Information:

MARK3 is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Several transcript variants encoding different isoforms have been found for this gene. MARK3 is also involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4. [provided by RefSeq, Oct 2011]

Target Class:

Kinase

Family:

CAMK

Sub Family:

Protein Ser/Thr

Protein Name:

MARK3

Protein Aliases:

C-TAK1|cTAK1|Cdc25C-associated protein kinase 1|ELKL motif kinase 2|EMK-2|Protein kinase STK10|Ser/Thr protein kinase PAR-1|Par-1a|Serine/threonine-protein kinase p78

Accession Number:

NM_002376.6

UniProt Number:

P27448

Gene Name:

MARK3

Gene ID:

4140

Gene Aliases:

CTAK1|KP78|PAR-1A

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

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Assay Information

Assay Type:

Enzymatic

Clinical Relevance

Therapeutic Area:

CNS/Addiction/Pain