MAP4K3, active

active MAP4K3. N-terminal GST-tagged and C-terminal 6His tagged, recombinant, human MAP4K3 amino acids 1-291.

Catalog #: 15-030


Biological Information
Background Information:
MAP4K3 is a member of the mitogen-activated protein Kinase kinase family. The encoded protein activates key effectors in cell Signaling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. Among its related pathways are TGF-Beta Pathway and Angiopoietin-like protein 8 regulatory pathway. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is MAP4K5.[provided by RefSeq, Jul 2012]
Target Class:
Ser/Thr Kinase
Accession Number:
GenBank NM_003618.2
Target Name:
Target Aliases:
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3, Germinal Center Kinase-Related Protein Kinase, MAPK/ERK Kinase Kinase Kinase 3, MEK Kinase Kinase 3, Germinal Center Kinase-Like Kinase
Target Species:
Product Type:
Drug Discovery & Development
Storage Conditions:
1 year at -70°C
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15-030x Datasheet

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