MAP Kinase 2/Erk2, unactive

N-terminal GST-tagged recombinant, murine full length p42 MAP kinase 2/Erk2.

Catalog #: 14-198


Biological Information
Background Information:
MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade also plays a role in initiation and regulation of meiosis, mitosis, and post-mitotic functions in differentiated cells by phosphorylating a number of transcription factors. About 160 substrates have already been discovered for ERKs.
Target Class:
Ser/Thr Kinase; MAPK; ERK subfamily
Accession Number:
Target Name:
Erk2 (MAPK1)
Target Aliases:
MAPK1, p40, PRKM2, MAPK2, PRKM1, p42-MAPK, p38, p41, ERK, ERK-2, ERT1, P42MAPK, p41mapk, ERK2
Target Species:
Product Type:
Drug Discovery & Development
Storage Conditions:
1 year at -20°C
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14-198x Datasheet

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