| Biological Information | |
|---|---|
| Background Information: | LKB1 is a tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Mutations in this gene have been associated with the autosomal dominant Peutz-Jeghers syndrome, as well as with skin, pancreatic, and testicular cancers.
GenBank NM000455 / GenBank AF308302 / GenBank NM_016289 |
| Target Class: | Kinase |
| Accession Number: | NM_000455.4 |
| Target Name: | LKB1 |
| Target Aliases: | STK11PJSLKB1 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
LKB1/STRADalpha/MO25alpha, active
N-terminal 6His-tagged recombinant, human full length LKB1. Provided as a complex with GST-STRADα and GST-MO25α.
Datasheets
14-596x Datasheet
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