Biological Information

Background Information:

LKB1 is a tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Mutations in this gene have been associated with the autosomal dominant Peutz-Jeghers syndrome, as well as with skin, pancreatic, and testicular cancers. GenBank NM000455 / GenBank AF308302 / GenBank NM_016289

Target Class:

Kinase

Family:

CAMK

Sub Family:

Protein Ser/Thr

Protein Name:

LKB1

Protein Aliases:

polarization-related protein LKB1

Accession Number:

NM_000455.4

UniProt Number:

Q15831

Gene Name:

STK11

Gene ID:

6794

Gene Aliases:

PJS|LKB1

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

6 months at -70°C

Usage disclaimer:

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Assay Information

Assay Type:

Enzymatic