LATS2, active

N-terminal GST-tagged recombinant, human LATS2 amino acids 553-end and N-terminal 6His-tagged recombinant, human MOBKL1A full length.

Catalog #: 14-987


Biological Information
Background Information:
LATS2 is a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. GenBank NM_014572.2 / GenBank BC038112
Target Class:
Accession Number:
NM_014572.2; BC038112.1
Target Name:
Target Species:
Product Type:
Drug Discovery & Development
Storage Conditions:
1 year at -70°C
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14-987x Datasheet

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