HIPK4, active

C-terminal 6His tagged, recombinant, human HIPK4 full length, expressed by baculovirus in Sf21 insect cells. Purified using immobilized metal affinity chromatography.

Catalog #: 15-003


Biological Information
Background Information:
HIPK4 (Homeodomain Interacting Protein Kinase 4) is a serine/threonine protein kinase that belongs to the HIPK (Homeodomain Interacting Protein Kinase) family of kinases. It is involved in the regulation of a variety of cellular processes, including transcriptional regulation, cell proliferation, and apoptosis. Research has suggested that HIPK4 plays a role in several diseases, including cancer and developmental disorders. In cancer, HIPK4 has been shown to promote tumor cell survival and proliferation, and alterations in HIPK4 expression and activity have been observed in various types of cancer. Additionally, HIPK4 has been implicated in the regulation of neural development and has been linked to developmental disorders such as autism spectrum disorder. HIPK4 has also been suggested as a potential therapeutic target in cancer, and efforts to develop small-molecule inhibitors of the kinase are underway.
Target Class:
Accession Number:
Target Name:
Target Species:
Product Type:
Drug Discovery & Development
Storage Conditions:
1 year at -70°C
Usage Disclaimer:
These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.


15-003x Datasheet

View Document