Biological Information

Background Information:

GRK7 (G Protein-Coupled Receptor Kinase 7) is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. It is specifically expressed in the retina and the encoded protein has been shown to phosphorylate cone opsins and initiate their deactivation. It involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO). GenBank NM_139209

Target Class:

Kinase

Family:

AGC

Sub Family:

Protein Ser/Thr

Protein Name:

GRK7

Protein Aliases:

G protein-coupled receptor kinase GRK7

Accession Number:

NM_139209.2

UniProt Number:

Q8WTQ7

Gene Name:

GRK7

Gene ID:

131890

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

6 months at -70°C

Usage disclaimer:

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Assay Information

Assay Type:

Enzymatic