EphA7, active

Background Information:

EphA7 (EPH Receptor A7) belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Increased expression of this gene is associated with multiple forms of carcinoma. GenBank NM_004440

Target Class:

Kinase

Family:

RTK

Sub Family:

Protein Tyrosine

Protein Name:

EphA7

Protein Aliases:

EPH homology kinase 3|EHK-3|EPH-like kinase 11|EK11|hEK11

Accession Number:

NM_004440.2

UniProt Number:

Q15375

Gene Name:

EPHA7

Gene ID:

2045

Gene Aliases:

Hek11

Target Species:

Human