Biological Information

Background Information:

DCAMKL2 is a protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. It may play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm (By similarity).

Target Class:

Kinase

Family:

CAMK

Sub Family:

Protein Ser/Thr

Protein Name:

DCAMKL2

Accession Number:

NM_001040260.1; NM_001040261.1

UniProt Number:

Q8N568

Gene Name:

DCLK2

Gene ID:

166614

Gene Aliases:

MGC45428|DCDC3|DCDC3B|DCK2

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

6 months at -70°C

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Assay Information

Assay Type:

Enzymatic

Clinical Relevance

Therapeutic Area:

CNS/Addiction/Pain