Biological Information
Background Information:
The ChemiSCREEN™ S1P2 Lysophospholipid Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of S1PR2 surface expression. ChemiSCREEN™ membrane preps can be used to screen for GPCR activity using GTPγS assays. Increased GPCR activation levels will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression.
Target Class:
GPCR
Family:
Lysophospholipid (S1P)
Sub Family:
Class A
Protein Name:
S1P2
Protein Aliases:
EDG5|Endothelial differentiation G-protein coupled receptor 5|Sphingosine 1-phosphate receptor Edg-5|S1P receptor Edg-5
Accession Number:
NM_004230
UniProt Number:
O95136
Gene Name:
S1PR2
Gene ID:
9294
Gene Aliases:
Gpcr13|H218|AGR16
Target Species:
Human
Cell Background:
Chem-1
Usage
Product Type:
Membrane Preparations
Application:
Drug Discovery & Development
Storage Conditions:
Vial to be stored at -70°C. Avoid repeat freeze/thaw cycles.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Type:
Cell Based
Assay Measures:
Binding & GTPγS Function
Detection Method:
Fluorescence, Radioactivity
Additional Information
Brand:
ChemiSCREEN™