Biological Information
Background Information:
The ChemiSCREEN™ S1P1 Lysophospholipid Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of S1PR1 surface expression. ChemiSCREEN™ membrane preps can be used to screen for GPCR activity using GTPγS assays. Increased GPCR activation levels will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression.
Target Class:
GPCR
Family:
Lysophospholipid (S1P)
Sub Family:
Class A
Protein Name:
S1P1
Protein Aliases:
EDG1|Endothelial differentiation G-protein coupled receptor 1|Sphingosine 1-phosphate receptor Edg-1|S1P receptor Edg-1|CD antigen CD363
Accession Number:
NM_001400
UniProt Number:
P21453
Gene Name:
S1PR1
Gene ID:
1901
Gene Aliases:
edg-1|D1S3362|CD363
Target Species:
Human
Cell Background:
Chem-1
Usage
Product Type:
Membrane Preparations
Application:
Drug Discovery & Development
Storage Conditions:
Vial to be stored at -70°C. Avoid repeat freeze/thaw cycles.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Type:
Cell Based
Assay Measures:
GTPγS Function
Detection Method:
Fluorescence, Radioactivity
Additional Information
Brand:
ChemiSCREEN™