ChemiSCREEN™ GABAB Receptor Membrane Preparation

Background Information:

The ChemiSCREEN™ GABAB Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of GABBR1 - GABBR2 surface expression. ChemiSCREEN™ membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression.

Target Class:

GPCR

Family:

GABAB

Sub Family:

Class C

Protein Name:

GABAB (B1/B2)

Protein Aliases:

GABA-B receptor

Accession Number:

NM_021903; NM_005458

UniProt Number:

Q9UBS5

Gene Name:

GABBR1

Gene ID:

2550

Gene Aliases:

hGB1a|GPRC3A

Target Species:

Human

Cell Background:

Chem-1