ChemiSCREEN™ CRF1 Receptor Membrane Preparation

Background Information:

The ChemiSCREEN™ CRF1 Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of CRHR1 surface expression. ChemiSCREEN™ membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression.

Target Class:

GPCR

Family:

Corticotropin-Releasing Factor

Sub Family:

Class B

Protein Name:

CRF1

Protein Aliases:

CRF-R1|CRFR-1|Corticotropin-releasing hormone receptor 1|CRH-R-1|CRH-R1

Accession Number:

X72304

UniProt Number:

P34998

Gene Name:

CRHR1

Gene ID:

1394

Gene Aliases:

CRF-R|CRF1

Target Species:

Human

Cell Background:

Chem-1