Biological Information

Background Information:

The ChemiSCREEN™ CB2 Cannabinoid Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of CNR2 surface expression. ChemiSCREEN™ membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach or to screen for GPCR activity using GTPγS assays. Increased binding affinities or GPCR activation levels will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression.

Target Class:

GPCR

Family:

Cannabinoid

Sub Family:

Class A

Protein Name:

CB2

Protein Aliases:

CB2|hCB2|CX5

Accession Number:

X74328

UniProt Number:

P34972

Gene Name:

CNR2

Gene ID:

1269

Gene Aliases:

CB2

Target Species:

Human

Cell Background:

Chem-4

Usage

Product Type:

Membrane Preparations

Application:

Drug Discovery & Development

Storage Conditions:

Vial to be stored at -70°C. Avoid repeat freeze/thaw cycles.

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Assay Information

Assay Type:

Cell Based

Assay Measures:

Binding

Detection Method:

Fluorescence, Radioactivity

Additional Information

Brand:

ChemiSCREEN™