Biological Information
Background Information:
The ChemiSCREEN™ CB2 Cannabinoid Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of CNR2 surface expression. ChemiSCREEN™ membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach or to screen for GPCR activity using GTPγS assays. Increased binding affinities or GPCR activation levels will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression.
Target Class:
GPCR
Family:
Cannabinoid
Sub Family:
Class A
Protein Name:
CB2
Protein Aliases:
CB2|hCB2|CX5
Accession Number:
X74328
UniProt Number:
P34972
Gene Name:
CNR2
Gene ID:
1269
Gene Aliases:
CB2
Target Species:
Human
Cell Background:
Chem-4
Usage
Product Type:
Membrane Preparations
Application:
Drug Discovery & Development
Storage Conditions:
Vial to be stored at -70°C. Avoid repeat freeze/thaw cycles.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Type:
Cell Based
Assay Measures:
Binding
Detection Method:
Fluorescence, Radioactivity
Additional Information
Brand:
ChemiSCREEN™