Biological Information
Background Information:
The ChemiSCREEN™ β2 Adrenergic Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of ADRB2 surface expression. ChemiSCREEN™ membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression.
Target Class:
GPCR
Family:
Adrenoceptor
Sub Family:
Class A
Protein Name:
beta2
Protein Aliases:
Beta-2 adrenoceptor
Accession Number:
NM_000024
UniProt Number:
P07550
Gene Name:
ADRB2
Gene ID:
154
Gene Aliases:
ADRBR|BAR|B2AR
Target Species:
Human
Cell Background:
Chem-2
Usage
Product Type:
Membrane Preparations
Application:
Drug Discovery & Development
Storage Conditions:
Vial to be stored at -70°C. Avoid repeat freeze/thaw cycles.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Type:
Cell Based
Assay Measures:
Binding
Detection Method:
Fluorescence, Radioactivity
Clinical Relevance
Therapeutic Area:
Inflammation/Allergy
Additional Information
Brand:
ChemiSCREEN™