ChemiSCREEN™ AT1 Angiotensin Receptor Membrane Preparation

Background Information:

The ChemiSCREEN™ AT1 Angiotensin Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of AGTR1 surface expression. ChemiSCREEN™ membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression.

Target Class:

GPCR

Family:

Angiotensin

Sub Family:

Class A

Protein Name:

AT1

Protein Aliases:

AT1BR|Angiotensin II type-1 receptor|AT1

Accession Number:

NM_000685

UniProt Number:

P30556

Gene Name:

AGTR1

Gene ID:

185

Gene Aliases:

AT1|AT2R1|AGTR1A|AT2R1A|HAT1R|AG2S|AT2R1B|AT1B

Target Species:

Human

Cell Background:

Chem-1