| Biological Information | |
|---|---|
| Background Information: | The ChemiScreen™ α2B Adrenergic Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of ADRA2B surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. |
| Target Class: | GPCR |
| Family: | Adrenoceptor |
| Accession Number: | NM_000682 |
| Target Name: | ADRA2B (α2B-adrenoceptor) |
| Target Aliases: | Adrenergic receptor alpha 2B, ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, FAME2, alpha-2BAR |
| Target Species: | Human |
| Cell Background: | Chem-1 |
| Usage | |
| Product Type: | Membrane Preparations |
| Application: | Drug Discovery & Development |
| Storage Conditions: | Vial to be stored at -70°C. Avoid repeat freeze/thaw cycles. |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
| Assay Information | |
| Assay Measures: | Binding |
| Detection Method: | FluorescenceRadioactivity |
| Additional Information | |
| Brand: | ChemiSCREEN™ |
ChemiScreen™ alpha2B Adrenergic Receptor Membrane Preparation
The ChemiScreen™ α2B Adrenergic Receptor Membrane Preparation measures ligand binding to ADRA2B GPCR via radioligand binding assays. Membrane preps contain 1mL of 1mg/mL frozen membranes.
Datasheets
HTS157M Datasheet
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