Biological Information

Background Information:

The ChemiSCREEN™ 5-HT6 Serotonin Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of HTR6 surface expression. ChemiSCREEN™ membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression.

Target Class:

GPCR

Family:

Serotonin

Sub Family:

Class A

Protein Name:

5-HT6

Protein Aliases:

5-HT6|Serotonin receptor 6

Accession Number:

NM_000871

UniProt Number:

P50406

Gene Name:

HTR6

Gene ID:

3362

Gene Aliases:

5-HT6|5-HT6R

Target Species:

Human

Cell Background:

Chem-1

Usage

Product Type:

Membrane Preparations

Application:

Drug Discovery & Development

Storage Conditions:

Vial to be stored at -70°C. Avoid repeat freeze/thaw cycles.

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Assay Information

Assay Type:

Cell Based

Assay Measures:

Binding

Detection Method:

Fluorescence, Radioactivity

Additional Information

Brand:

ChemiSCREEN™