| Biological Information | |
|---|---|
| Background Information: | Casein Kinase 2 Alpha 2 is a catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. It phosphorylates acidic proteins such as casein, and is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythms. This heterotetrameric kinase includes two catalytic subunits, either alpha or alpha', and two regulatory beta subunits. The closely related gene paralog encoding the alpha, or alpha 1 subunit (CSNK2A1, Gene ID: 1457) is found on chromosome 20. An intronic variant in this gene (alpha 2) may be associated with leukocyte telomere length in a South Asian population. A related transcribed pseudogene is found on chromosome 11.
GenBank NM_001896 |
| Target Class: | Kinase |
| Accession Number: | NM_001896.2 |
| Target Name: | CK2α2 |
| Target Aliases: | CSNK2A2, CK2A2, CSNK2A1, FLJ43934 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -70°C |
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Casein Kinase 2alpha2, active
N-terminal 6His-tagged recombinant, human full length Casein Kinase 2α2.
Datasheets
14-689x Datasheet
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