cAMP Hunter™ eXpress PPYR1 (NPY4R) CHO-K1 GPCR Assay

The cAMP Hunter™ eXpress PPYR1 (NPY4R) CHO-K1 GPCR Assay measures PPYR1 (GPCR) activity via decreased levels of intracellular cAMP. eXpress kits contain all assay materials: cells, reagents, and plates.

Catalog #: 95-0087E2CP2L


Biological Information
Background Information:
The cAMP Hunter™ PPYR1 (NPY4R) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. pancreatic polypeptide, peptide YY) based activation of PPYR1 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type PPYR1, a naturally Gi/Go coupled GPCR. Upon activation of PPYR1, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.
Target Class:
Neuropeptide Y Receptors
Sub Family:
Class A
Accession Number:
Target Name:
Target Aliases:
Pancreatic polypeptide receptor 1
Target Species:
Cell Background:
Product Type:
eXpress Assay Kits
Drug Discovery & Development
Storage Conditions:
Store in vapor phase of liquid nitrogen.
Usage Disclaimer:
Ready-to-use eXpress assay kits are intended for in vitro research purposes only. These kits are not suitable for lot release applications. Refer to the ready-to-use bioassay kit format for potency testing in lot release for biologic therapeutics. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Type:
Assay Measures:
cAMP Detection
Detection Method:
Additional Information
cAMP Hunter™

User Manuals & Protocols

70-234 cAMP Hunter eXpress GPCR Assay REV10 User Manual

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95-0087E2 x Datasheet

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