cAMP Hunter™ CHO-K1 NPY2R Bioassay Kit

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The cAMP Hunter™ CHO-K1 NPY2R Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. peptide YY) based activation of NPY2R GPCR activity via detection of levels of intracellular cAMP.

Catalog #: 95-0077Y2-00055

$1,989.00 – $8,979.00

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Biological Information
Background Information:
The cAMP Hunter™ CHO-K1 NPY2R Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. peptide YY) based activation of NPY2R GPCR activity via detection of levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type NPY2R, a naturally Gi coupled GPCR. Upon activation of NPY2R, the (decrease/increase) in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates.
Target Class:
GPCR
Family:
Neuropeptide Y Receptors
Sub Family:
Class A
Accession Number:
AY236540
Target Name:
NPY2R
Target Aliases:
Neuropeptide Y receptor Y2, NPY2-R, Neuropeptide Y2 receptor
Target Species:
Human
Cell Background:
CHO-K1
Usage
Product Type:
Bioassay Kits
Application:
Potency; Commercial Release & Stability
Kit Components:
Storage Conditions:
Store in vapor phase of liquid nitrogen.
Usage Disclaimer:
These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Type:
Functional
Assay Measures:
cAMP Detection
Detection Method:
Chemiluminescence
Additional Information
Brand:
cAMP Hunter™

User Manuals & Protocols

70-366 cAMP Hunter NPY2R Bioassay Kit REV1 User Manual

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Datasheets

95-0077Y2x Datasheet

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