| Biological Information | |
|---|---|
| Background Information: | The cAMP Hunter™ CHO-K1 LHCGR Bioassay Kit an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. HLH) based activation of LHCGR activity via detection of levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type LHCGR, a Gαs-coupled receptor. Upon activation of LHCGR, the (decrease/increase) in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. |
| Target Class: | GPCR |
| Family: | Glycoprotein Hormone Receptors |
| Accession Number: | NM_000233 |
| Target Name: | LHCGR |
| Target Aliases: | Choriogonadotropin receptorHHGLHRLCGRLGR2ULG5LHRHRLSH-RLH/CGRLH/CG-R |
| Target Species: | Human |
| Cell Background: | CHO-K1 |
| Usage | |
| Product Type: | Bioassay Kits |
| Application: | Potency, Commercial Release & Stability |
| Kit Components: |  |
| Storage Conditions: | Short term (24 h): Store in vapor phase of liquid nitrogen. |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
| Assay Information | |
| Assay Type: | Functional |
| Assay Measures: | cAMP Detection |
| Detection Method: | Chemiluminescence |
| Additional Information | |
| Brand: | cAMP Hunter™ |
cAMP Hunter CHO-K1 LHCGR Bioassay Kit
The cAMP Hunter™ CHO-K1 LHCGR Bioassay Kit an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. HLH) based activation of LHCGR activity via detection of levels of intracellular cAMP
User Manuals & Protocols
70-416 cAMP Hunter CHO-K1 LHCGR Bioassay Kit User Manual Rev0
View DocumentDatasheets
95-0106Y2x Datasheet
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