CaM Kinase IIgamma, active

Background Information:

CaMK IIγ is a Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplasmic reticulum Ca(2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, it involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In the central nervous system, it is involved in the regulation of neurite formation and arborization. GenBank NM_172171

Target Class:

Kinase

Family:

CAMK

Sub Family:

Protein Ser/Thr

Protein Name:

CaMK2gamma

Protein Aliases:

CaMK-II subunit gamma

Accession Number:

NM_172171.1

UniProt Number:

Q13555

Gene Name:

CAMK2G

Gene ID:

818

Gene Aliases:

CAMK|CAMK-II|CAMKG

Target Species:

Human