Biological Information | |
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Background Information: | ARK5 (AMPK related kinase 5) is a serine/threonine kinase and a member of the AMPK family of protein kinases. In response to stimulation by Akt, ARK5 prevents cell death induced by glucose starvation and death receptor activation in tumor cells as a result of inhibition of caspase 8 activation via preservation of c-FLIP. ARK5 can also negatively regulate procaspase-6 via direct phosphorylation at Ser257, leading to resistance to the FasL/Fas signaling system.
GenBank NM_014840 |
Target Class: | Kinase |
Accession Number: | NM_014840.2 |
Target Name: | NuaK1 (ARK5) |
Target Aliases: | NUAK1KIAA0537ARK5NuaK1 |
Target Species: | Human |
Usage | |
Product Type: | Enzymes |
Application: | Drug Discovery & Development |
Storage Conditions: | 6 months at -70°C |
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