| Biological Information | |
|---|---|
| Background Information: | ARK5 (AMPK related kinase 5) is a serine/threonine kinase and a member of the AMPK family of protein kinases. In response to stimulation by Akt, ARK5 prevents cell death induced by glucose starvation and death receptor activation in tumor cells as a result of inhibition of caspase 8 activation via preservation of c-FLIP. ARK5 can also negatively regulate procaspase-6 via direct phosphorylation at Ser257, leading to resistance to the FasL/Fas signaling system.
GenBank NM_014840 |
| Target Class: | Kinase |
| Accession Number: | NM_014840.2 |
| Target Name: | NuaK1 (ARK5) |
| Target Aliases: | NUAK1KIAA0537ARK5NuaK1 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
ARK5, active
N-terminal 6His-tagged recombinant, human ARK5 amino acids 2-end.
Datasheets
14-661x Datasheet
View Document