| Biological Information | |
|---|---|
| Background Information: | ErbB2 is a member of the EGFR family that has no ligand binding domain on its own but forms heterodimers with other ligand-binding family members. ErbB2 overexpression/gene amplification has been associated with many types of cancers. Trastuzumab is a humanized IgG1 monoclonal antibody that targets the HER2 receptor (also known as HER2/neu) that is found on the cell membrane of epithelial cells. HER2 plays an important role in normal cell growth and differentiation. |
| Family: | Receptor Typosine Kinase (RTK): Growth Factor Receptor |
| Target Name: | ErbB2 |
| Usage | |
| Product Type: | Antibodies |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 4°C. Please avoid multiple freeze/thaw cycles. |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
| Additional Information | |
| Brand: | DiscoverX |
Anti-ErbB2 Monoclonal Antibody (trastuzumab)
ErbB2 is a member of the EGFR family that has no ligand binding domain on its own but forms heterodimers with other ligand-binding family members.
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92-1359 Datasheet
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