Biological Information
Background Information:
CTLA4, or CTLA-4 is also known as cytotoxic T-lymphocyte-associated protein 4 or CD152. This monoclonal antibody binds human CTLA4, which functions as a immune checkpoint receptor that downregulates the immune system. CTLA4 is expressed on activated T cells and binds the B7 family members, CD80 (B7-1) and CD86 (B7-2), and the protein restricts the progression of T cells to an activated state by inhibiting IL-2 secretion and cellular proliferation. Provided as 100 μg of antibody in buffer.
Target Class:
Checkpoint Receptor
Family:
IgSF
Sub Family:
Immune Inhibitory Receptor
Usage
Product Type:
Antibodies
Application:
Drug Discovery & Development
Storage Conditions:
Store at -20°C. Please avoid multiple freeze/thaw cycles.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Additional Information
Brand:
Eurofins DiscoverX®